Comparison
of the Midazolam Transnasal
Atomizer and Oral Midazolam For Sedative
Premedication in Paediatric Cases
Published: October 1, 2011 | DOI: https://doi.org/10.7860/JCDR/2011/.1550
Ramesh Koppal, Adarsh E.S., Uday Ambi, Anilkumar G.
MD, Associate Professor, Dept. of Anaesthesiology,
SN Medical College and HSK Hospital, Bagalkot,
Karnataka, India.
MD, Assistant Professor, Dept. of Anaesthesiology,
SN Medical College and HSK Hospital, Bagalkot,
Karnataka, India.
MD, Assistant Professor, Dept. of Anaesthesiology,
SN Medical College and HSK Hospital, Bagalkot,
Karnataka, India.MD, Assistant Professor, Dept. of Anaesthesiology,
SN Medical College and HSK Hospital,
Bagalkot, Karnataka, India.
Correspondence
Ramesh Koppal,
Associate Professor, Dept. of Anaesthesiology,
SN Medical College and HSK Hospital,
Bagalkot, Karnataka, India-587101.
Phone: +919845504515
E-mail: rameshkoppaldr@rediffmail.com
Background: The role of effective premedication in children is of utmost importance in the conduct of paediatric anaesthesia. Midazolam is a proven and safe sedative anxiolytic in the paediatric group.
Objective: To evaluate the safety and effectiveness of Midazolam by the transnasal and oral routes for paediatric sedation.
Materials and Methods: We evaluated 60 ASA grade I and II children who were randomized to receive either oral (0.5mg/kg)or transnasal (0.5mg/kg) midazolam. The demographic details, the sedation score and the separation score were noted by a blinded observer and were statistically analysed.
Results: Both the routes were equally effective in achieving the adequate sedation and the separation scores. The transnasal route showed a faster onset of the adequate sedation scores. The oral route was better accepted by children.
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